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1.
Rev Rene (Online) ; 25: e92175, 2024. tab, graf
Artículo en Portugués | LILACS-Express | LILACS, BDENF - Enfermería | ID: biblio-1535057

RESUMEN

RESUMO Objetivo analisar as tendências investigativas de teses e dissertações sobre COVID-19 dos programas de pós-graduação da área da Enfermagem no Brasil. Métodos estudo bibliométrico realizado no Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, com análise de dados bibliométricos por meio do IRAMUTEQ. Resultados 82 trabalhos foram selecionados, sendo a maioria dissertações (87,8%). Foram distribuídos em seis classes: 1) Saúde mental dos profissionais de enfermagem; 2) Saúde da mulher grávida e puérpera; 3) Adaptação do atendimento às pessoas em situação de vulnerabilidade; 4) Ser humano e ser enfermeiro: convivendo e enfrentando o vírus; 5) Reorganização do trabalho da enfermagem; e 6) Repercussões da COVID-19 para a enfermagem. Conclusão as pesquisas estão concentradas nas condições de trabalho da enfermagem, na saúde mental e na reorganização dos fluxos de atendimento. Contribuições para a prática: o estudo promove visibilidade à produção de conhecimento em Enfermagem no contexto da pandemia de COVID-19 no Brasil e identifica lacunas para futuros estudos.


ABSTRACT Objective to analyze the investigative trends of theses and dissertations on COVID-19 from graduate programs in Nursing in Brazil. Methods a bibliometric study conducted using the Theses and Dissertations Catalog from the Coordination for the Improvement of Higher Education Personnel, with bibliometric data analysis through IRAMUTEQ. Results 82 works were selected, with the majority being dissertations (87.8%). They were distributed into six classes: 1) Nursing professionals' mental health. 2) Pregnant and postpartum women health. 3) Adaptation of care for people in vulnerable situations. 4) Human being and being a nurse: living and facing the virus. 5) Nursing work reorganization, and 6) COVID-19 repercussions for nursing. Conclusion research is concentrated on nursing working conditions, mental health, and the care workflows reorganization. Contributions to practice: the study brings visibility to the knowledge production in Nursing within the context of the COVID-19 pandemic in Brazil and identifies gaps for future studies.

2.
Rev. colomb. anestesiol ; 51(4)dic. 2023.
Artículo en Inglés | LILACS-Express | LILACS | ID: biblio-1535702

RESUMEN

Introduction Anesthetists play an important role during interventional radiology procedures. Like the main operator, anesthetists may also be subject to significant radiation levels in the fluoroscopy suite. Due to its complexity, hepatic chemoembolization procedures demand high fluoroscopic times and digital subtraction angiography images, exposing patients and medical staff to high radiation doses. Objective To assess and quantify the radiation to which one anesthetist was exposed over the course of seven consecutive hepatic chemoembolization procedures, and compare it to the exposure received by the main operator. Methods Medical staff dosimetry was evaluated during seven consecutive hepatic chemoembolization procedures conducted in a private hospital in Recife (Brazil), using thermoluminiscent dosimeters placed in regions of the head and torso. Results For the seven procedures evaluated in this study, the anesthetist received, on average, absorbed doses to the glabella, left eyebrow, right eyebrow and effective dose of 142.4 ± 72 µSv, 117.3 ± 66 µSv, 137.8 ± 71 µSv and 12.4 ± 8.4 µSv, respectively. Conclusions In some cases, ocular dose and effective dose received by the anesthetist may be 4 and 4.7 times greater, respectively, when compared to the main operator. According to the results of this study, the current occupational annual dose limit to the lens of the eye of 20 mSv can be exceeded with only two hepatic chemoembolization procedures per week if adequate radiation protection conditions are not guaranteed.


Introducción El anestesiólogo desempeña un papel importante durante los procedimientos de radiología intervencionista. Al igual que el operador principal, el anestesiólogo también puede estar expuesto a niveles significativos de radiación en la sala de fluoroscopía. Debido a su complejidad, durante los procedimientos de quimioembolización hepática se deben utilizar imágenes de fluoroscopía y angiografía de sustracción digital por períodos prolongados, exponiendo a los pacientes y al personal médico a dosis elevadas de radiación. Objetivo Evaluar y cuantificar la radiación a la cual se expuso un anestesiólogo durante el transcurso de siete procedimientos consecutivos de quimioembolización hepática, y comparar con la exposición recibida por el operador principal. Métodos Evaluación de la dosimetría ocupacional durante siete procedimientos consecutivos de quimioembolización hepática realizados en un hospital privado de Recife (Brasil) por medio de dosímetros termoluminiscentes ubicados en regiones de la cabeza y el torso. Resultados Para los siete procedimientos evaluados en este estudio, el anestesiólogo recibió, en promedio, dosis absorbidas en el entrecejo, la ceja izquierda, la ceja derecha y dosis efectivas de 142,4 ± 72 µSv, 117,3 ± 66 µSv, 137,8 ± 71 µSv y 12,4 ± 8,4 µSv, respectivamente. Conclusiones En algunos casos, la dosis ocular y la dosis efectiva que recibe el anestesiólogo puede ser, respectivamente, entre 4 y 4,7 veces más alta que la que recibe el operador principal. De acuerdo con los resultados de este estudio, el límite ocupacional anual de dosis en cristalino (20 mSv) se puede superar con apenas dos procedimientos de quimioembolización hepática a la semana en caso de no garantizarse las condiciones adecuadas de protección contra la radiación.

3.
Int Urol Nephrol ; 55(10): 2397-2404, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37442905

RESUMEN

PURPOSE: Several clinical scenarios regulate the final ejaculated semen, which is pivotal to reproductive success. Sperm motility and plasma membrane fusogenic activity primarily rely on the peculiar sperm lipid composition, influenced by the patient's metabolism, genetics, nutritional, environmental status, and concomitant clinical entities such as varicocele. This study aimed to determine the relationship between serum lipid profile and testicular function (semen quality and testosterone levels). METHODS: This retrospective study uses medical charts of 278 infertile men who attended andrological care between 2000 and 2019. Seminal analysis data, lipid profile, and total serum testosterone were collected. A multiple linear regression analysis was performed to evaluate the influence of the lipid parameters on the seminal variables. Statistical analyses were carried out with p ≤ 0.05 considered statistically significant. RESULTS: Seminal creatine kinase activity (p = 0.024) is negatively related to HDL (p = 0.032) and triglycerides (p = 0.037), while total testosterone (p < 0.0001) and seminal volume (p = 0.046) appeared both to be negatively related to triglycerides (p = 0.030 and p = 0.033, respectively). CONCLUSION: Medical advice commonly advocated to prevent endothelial dysfunction and cardiovascular disease and improve HDL-cholesterol and triglyceride levels in dyslipidemic patients should also be given to infertile men. Physicians should give patients a thorough assessment, including the blood lipid profile, hormonal status, and routine seminal examinations. We propose a more comprehensive men´s health check-up for the infertile male population, not limited to a simple evaluation of basic sperm parameters.


Asunto(s)
Infertilidad Masculina , Análisis de Semen , Masculino , Humanos , Semen , Salud del Hombre , Recuento de Espermatozoides , Estudios Retrospectivos , Motilidad Espermática/fisiología , Lípidos , Triglicéridos , Testosterona
4.
BMC Complement Med Ther ; 23(1): 154, 2023 May 11.
Artículo en Inglés | MEDLINE | ID: mdl-37170258

RESUMEN

BACKGROUND: Stroke is a leading cause of death and disability worldwide. A major factor in brain damage following ischemia is excitotoxicity caused by elevated levels of the neurotransmitter glutamate. In the brain, glutamate homeostasis is a primary function of astrocytes. Amburana cearensis has long been used in folk medicine and seed extract obtained with dichloromethane (EDAC) have previously been shown to exhibit cytoprotective activity in vitro. The aim of the present study was to analyse the activity of EDAC in hippocampal brain slices. METHODS: We prepared a dichloromethane extract (EDAC) from A. cearensis seeds and characterized the chemical constituents by 1H and 13C-NMR. Hippocampal slices from P6-8 or P90 Wistar rats were used for cell viability assay or glutamate uptake test. Hippocampal slices from P10-12 transgenic mice SOX10-EGFP and GFAP-EGFP and immunofluorescence for GS, GLAST and GLT1 were used to study oligodendrocytes and astrocytes. RESULTS: Astrocytes play a critical role in glutamate homeostasis and we provide immunohistochemical evidence that in excitotoxicity EDAC increased expression of glutamate transporters and glutamine synthetase, which is essential for detoxifying glutamate. Next, we directly examined astrocytes using transgenic mice in which glial fibrillary acidic protein (GFAP) drives expression of enhanced green fluorescence protein (EGFP) and show that glutamate excitotoxicity caused a decrease in GFAP-EGFP and that EDAC protected against this loss. This was examined further in the oxygen-glucose deprivation (OGD) model of ischemia, where EDAC caused an increase in astrocytic process branching, resulting in an increase in GFAP-EGFP. Using SOX10-EGFP reporter mice, we show that the acute response of oligodendrocytes to OGD in hippocampal slices is a marked loss of their processes and EDAC protected oligodendrocytes against this damage. CONCLUSION: This study provides evidence that EDAC is cytoprotective against ischemia and glutamate excitotoxicity by modulating astrocyte responses and stimulating their glutamate homeostatic mechanisms.


Asunto(s)
Astrocitos , Ácido Glutámico , Ratas , Ratones , Animales , Ácido Glutámico/metabolismo , Ratas Wistar , Cloruro de Metileno/metabolismo , Hipocampo/metabolismo , Isquemia/metabolismo , Ratones Transgénicos , Oxígeno/metabolismo , Extractos Vegetales/farmacología , Extractos Vegetales/metabolismo , Homeostasis , Oligodendroglía/metabolismo , Semillas
5.
ACS Omega ; 8(20): 17800-17808, 2023 May 23.
Artículo en Inglés | MEDLINE | ID: mdl-37251174

RESUMEN

In this work, we synthesized and studied the spectroscopic properties of (NH4)2(SO4)2Y(H2O)6 (Y = Ni, Mg) crystals doped with AgNO3 or H3BO3. These crystals constitute a series of hexahydrated salts known as Tutton salts. We investigated the influence of dopants on the vibrational modes of the tetrahedral ligands NH4 and SO4, octahedral complexes Mg(H2O)6 and Ni(H2O)6, and H2O molecules present in these crystals through Raman and infrared spectroscopies. We were able to identify bands that are attributed to the presence of Ag and B dopants, as well as band shifts caused by the presence of these dopants in the crystal lattice. A detailed study of the crystal degradation processes was performed by thermogravimetric measurements, where there was an increase in the initial temperature of crystal degradation due to the presence of dopants in the crystal lattice. Raman spectroscopy of the crystal residues after the thermogravimetric measurements helped us to elucidate the degradation processes occurring after the crystal pyrolysis process.

8.
Spectrochim Acta A Mol Biomol Spectrosc ; 284: 121753, 2023 Jan 05.
Artículo en Inglés | MEDLINE | ID: mdl-36058169

RESUMEN

Gold nanoparticles (AuNPs) are attractive structures for biosensing, most due to different properties at nanoscale and biocompatibility. Localized surface plasmon resonance (LSPR) is one of these properties; LSPR enable the electromagnetic field enhancement closer to metallic surface, which allows surface-enhanced spectroscopies, like surface enhanced fluorescence (SEF). In this study, an immuno-biosensor based on gold nanorods (AuNRs) and SEF was constructed for simple and fast analysis to detect albumin antibody (anti-BSA) using antigen-antibody (anti-BSA/BSA) interaction as the biorecognition model. AuNRs were presented in two distinct configurations, in suspension (S-AuNRs) and adsorbed on glass slides (AuNRs-chip), and the detection was performed through an extrinsic method, wherein the SEF signal of a reporter molecule (IR-820 cyanine-type dye) was monitored. The analyte detection was evidenced by SEF mapping, where the average signal in the presence of anti-BSA was three times more intense than for the assay in the absence of analyte. A digital protocol was proposed to simplify the spectroscopic data analysis and reduce the intensity variability; in this protocol the number of positive events in the presence of anti-BSA is much larger (around two times) compared to the absence of analyte. The AuNRs based SEF immuno-biosensor allowed an efficient and simple analysis with specific biorecognition and may contribute as an efficient spectroscopy platform for immuno-biosensing.


Asunto(s)
Técnicas Biosensibles , Nanopartículas del Metal , Nanotubos , Albúminas , Técnicas Biosensibles/métodos , Oro/química , Nanopartículas del Metal/química , Nanotubos/química , Resonancia por Plasmón de Superficie/métodos
9.
Texto & contexto enferm ; 32: e20230072, 2023. tab
Artículo en Inglés | LILACS-Express | LILACS, BDENF - Enfermería | ID: biblio-1450585

RESUMEN

ABSTRACT Objective: to analyze associations between moral distress and ethical issues experienced by nurses during COVID-19. Method: this is a quantitative, cross-sectional study, carried out with 101 nurses working in university hospitals, between March and May 2022, through socio-occupational issues, ethical implications that lead to moral distress, and the Ethical Issues Experienced by Nurses in Emergency Questionnaire, adapted and validated for Brazilians. Descriptive statistics, ANOVA, Pearson's chi-square and multiple linear regression were used, and p<0.05 was adopted. Results: the 9 elements attributed to ethical implications were classified with some degree of importance for moral distress, with the highest average in the following items: I feel a commitment, responsibility and moral obligation to provide care to the infected population (4.26) and I have the knowledge or experience to work on the frontline of COVID-19 (3.44). The association of moral distress with ethical issues showed that individuals who attributed high importance to ethical implications also had ethical issues at a moderate/high level, emphasizing a higher mean in questions of "patient care" (4.07). It was evident that participants' moral distress was more affected by the following constructs: "perception of hospital measures against COVID-19" (p=.000), "ethical issues in patient care" (p=.000) and "perception of social stigmatization" (p=.000). Conclusion: when relating ethical issues to moral distress, it was possible to show that COVID-19 generated an abrupt change in nurses' work routine, which hinders adequate decision-making in situations involving issues beyond care, but also at a professional and organizational level, leading to the experience of moral distress.


RESUMEN Objetivo: analizar asociaciones entre sufrimiento moral y problemas éticos vividos por enfermeros durante la COVID-19. Método: estudio cuantitativo, transversal, realizado con 101 enfermeros que actúan en hospitales universitarios, entre marzo y mayo de 2022, a través de cuestiones sociolaborales, implicaciones éticas que conducen al sufrimiento moral y del Ethical Issues Experienced by Nurses in Emergency Questionnaire, adaptado y validado para brasileños. Se utilizó estadística descriptiva, ANOVA, chi-cuadrado de Pearson y regresión lineal múltiple, y se adoptó p<0,05. Resultados: los 9 elementos atribuidos a implicaciones éticas fueron clasificados con algún grado de importancia para el sufrimiento moral, con mayor promedio en los siguientes ítems: Siento compromiso, responsabilidad y obligación moral de brindar atención a la población infectada (4,26) y tengo conocimiento o experiencia para actuar en la primera línea de COVID-19 (3,44). La asociación del sufrimiento moral con los problemas éticos mostró que los individuos que atribuían alta importancia a las implicaciones éticas también presentaban problemas éticos en un nivel moderado/alto, destacando un promedio más alto en cuestiones de "atención al paciente" (4,07). Se evidenció que el malestar moral de los participantes se vio más afectado por los siguientes constructos: "percepción de las medidas hospitalarias frente al COVID-19" (p=,000), "problemas éticos en la atención al paciente" (p=.000) y "percepción de estigmatización social" (p=,000). Conclusión: al relacionar los problemas éticos con el sufrimiento moral, se pudo evidenciar que el COVID-19 generó un cambio abrupto en la rutina de trabajo de los enfermeros, lo que dificulta la toma de decisiones adecuadas en situaciones que involucran cuestiones más allá del cuidado, pero también a nivel profesional y organizacional que lleva a la experiencia del sufrimiento moral.


RESUMO Objetivo: analisar associações entre sofrimento moral e problemas éticos vivenciados por enfermeiros durante à COVID-19. Método: estudo quantitativo, transversal, realizado com 101 enfermeiros atuantes em hospitais universitários entre março e maio de 2022, por meio de questões sociolaborais, implicações éticas que levam ao sofrimento moral e do Ethical Problems Experienced By Nurses In Emergency Questionnaire adaptado e validado para brasileiros. Empregou-se estatística descritiva, ANOVA, Qui-quadrado de Pearson e regressão linear múltipla, e adotou-se p<0,05. Resultados: os 09 elementos atribuídos às implicações éticas foram classificados com algum grau de importância para o sofrimento moral, apresentando maior média nos seguintes itens: sinto compromisso, responsabilidade e obrigação moral em prestar cuidados à população infectada (4,26) e possuo conhecimento ou experiência para atuar na linha de frente à COVID-19 (3,44). A associação do sofrimento moral aos problemas éticos demonstrou que os indivíduos que atribuíram alta importância às implicações éticas também apresentavam problemas éticos em nível moderado/alto, ressaltando maior média nas questões de "cuidado ao paciente" (4,07). Evidenciou-se que o sofrimento moral dos participantes foi mais afetado pelos seguintes construtos: "percepção das medidas hospitalares contra a COVID-19" (p=,000), "problemas éticos no atendimento a pacientes" (p=,000) e "percepção da estigmatização social" (p=,000). Conclusão: ao relacionar os problemas éticos ao sofrimento moral, foi possível evidenciar que a COVID-19 gerou uma mudança abrupta na rotina de trabalho dos enfermeiros, o que dificulta a tomada de decisão adequada diante situações que envolve questões além do cuidado, mas também em nível profissional e organizacional levando a vivência de sofrimento moral.

10.
Phys Chem Chem Phys ; 24(44): 27449-27458, 2022 Nov 18.
Artículo en Inglés | MEDLINE | ID: mdl-36341946

RESUMEN

The present study reports a direct approach to generate efficient hot spots using a nonresonant molecule bound to the inner part or hot spots that can increase the SERS sensitivity to obtain spectra of one and a few molecules. The 4-Mercaptobenzoic acid (4-MBA) adsorbate, connected to the Ag surface by a thiolate-Ag bonding, was able to trigger a self-assembly process of AgNP, which occurred by cooperative hydrogen bonds between the carboxylic groups of 4-MBA located in different nanoparticles when the pH was adjusted to 4. The self-assembly structure was characterized by UV-Vis spectroscopy and SERS (Surface Enhancement Raman Scattering), and DFT-based calculation of the model complex [AgNP-(4-MBA)2-AgNP] was employed to improve the understanding of the self-assembled complex formation through the comparison of calculated and experimental SERS spectra. The SERS signal of 4-MBA on AgNP above the pKa of the carboxyl group was not observed below 1 × 10-6 mol L-1 in any condition. Additionally, the SERS spectra of 4-bromobezenothiol (4-BrBT) at 5.0 × 10-7 mol L-1 had no bands assignable to 4-BrBT, reinforcing the hypothesis that the SERS intensification for 4-MBA in low concentrations (below 1 × 10-6 mol L-1) is due to the hydrogen bonding triggered self-assembly of AgNP below 4-MBA pKa. The average SERS of the 4-MBA in low surface coverage shows a mixture of structures, such as protonated and deprotonated 4-MBA, as well as a small amount of benzenethiol coming from decarboxylation of part of 4-MBA molecules. The few molecules SERS detection of 4-MBA was demonstrated experimentally and the experimental results were associated with a greater number of hot spots formed, being befitting with the generalized Mie theory simulations.

11.
Front Reprod Health ; 4: 820451, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36303626

RESUMEN

Marijuana is one of the most consumed drugs worldwide. There is increasing evidence of an association between marijuana and male infertility. This study intends to assess the repercussion of marijuana smoking and other habits (sedentary lifestyle, alcohol, and tobacco use) in the testicular function of infertile men seeking andrological evaluation. A retrospective study was performed using medical records data of men aged 18-59 years from 2009 to 2017. Complete semen analyses, sperm functional tests, SHBG, and hormonal levels, testosterone-to-estradiol ratio (T/E2), and testis volume were evaluated. Exclusion criteria included cryptorchidism, infertility caused by genetic or infectious diseases, and cancer. A multiple linear regression analysis was performed to investigate which habit could predict certain parameters using the software SPSS 23.0 (P < 0.05). In a sample of 153 men, semen parameters, testosterone levels, and testis volume were not significantly influenced. Marijuana use had the broader hormonal changes since it influences estradiol (P = 0.000; B = -11.616), prolactin (P = 0.000; B = 3.211), SHBG levels (P = 0.017; B = 7.489), and T/E2 (P = 0.004; B = 14.030). Sedentary lifestyle (P = 0.028; B = 1.279) and tobacco smoking (P = 0.031; B = -2.401) influenced the prolactin levels. Marijuana is associated with hormonal imbalance in this infertile cohort by lowering estradiol levels and inhibiting aromatase function.

12.
An. bras. dermatol ; 97(5): 628-636, Sept.-Oct. 2022. tab, graf
Artículo en Inglés | LILACS-Express | LILACS | ID: biblio-1403146

RESUMEN

Abstract Background: Nevus sebaceous of Jadassohn is defined as a rare congenital malformation characterized as a non-hereditary hamartoma of the adnexal structures of the skin. Its etiology is not yet well understood, but it is believed to be related to post-zygotic mutations in the HRAS, NRAS and KRAS genes. Objective: To describe the clinical manifestation of nevus sebaceous, as well as the main management techniques addressed in the medical literature. Moreover, the present study discusses a case report of a congenital linear nevus in the left retroauricular region found in a male patient, without extracutaneous manifestations. Method: A narrative review of the literature was carried out. Discussion: Nevus sebaceous occurs as lesions with a linear or oval appearance, with a smooth or verrucous texture, generally alopecic and with very variable color. Moreover, nevus sebaceous is one of the components of the so-called linear nevus syndrome or Schimmelpenning-Feuerstein-Mims syndrome, which is associated with multisystemic complications. The treatment of the lesions is still controversial; however, most experts indicate surgical excision as the most frequently adopted treatment method, in addition to multidisciplinary follow-up when the diagnosis of Schimmelpenning-Feuerstein-Mims syndrome is established. Conclusion: The linear nevus syndrome constitutes a rare manifestation; however, its diagnosis should be considered in children born with nevus sebaceous. There is no consensus yet on the best therapy, but surgical removal has shown to be a viable option.

13.
Psychiatry Res ; 317: 114835, 2022 11.
Artículo en Inglés | MEDLINE | ID: mdl-36166946

RESUMEN

This study aimed to evaluate markers of the CLOCK gene rs1801260 and rs4864548 in Mexican adolescents, addressing clinical and biological aspects previously associated with ADHD. 347 Mexican adolescents were assessed for mental disorders, metabolic disruption and related conditions, circadian preference, as well as genotyping for the CLOCK. We found a significant association between ADHD and the AA and AG genotypes of rs1801260. Also, we identified in the ADHD group that the total Triiodothyronine and total Thyroxine values were respectively 10 ng/dl units and 0.58 ug/dl units lower in females than in males. Previously reported common variations of the CLOCK gene have been associated with ADHD like the Rs1801260 polymorphism hereby we could consider it as risk factor, but genetic, biochemical and clinical studies in the Mexican population are entailed.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad , Proteínas CLOCK , Adolescente , Femenino , Humanos , Masculino , Trastorno por Déficit de Atención con Hiperactividad/genética , Proteínas CLOCK/genética , Genotipo , Polimorfismo de Nucleótido Simple/genética
14.
An Bras Dermatol ; 97(5): 628-636, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35863943

RESUMEN

BACKGROUND: Nevus sebaceous of Jadassohn is defined as a rare congenital malformation characterized as a non-hereditary hamartoma of the adnexal structures of the skin. Its etiology is not yet well understood, but it is believed to be related to post-zygotic mutations in the HRAS, NRAS and KRAS genes. OBJECTIVE: To describe the clinical manifestation of nevus sebaceous, as well as the main management techniques addressed in the medical literature. Moreover, the present study discusses a case report of a congenital linear nevus in the left retroauricular region found in a male patient, without extracutaneous manifestations. METHOD: A narrative review of the literature was carried out. DISCUSSION: Nevus sebaceous occurs as lesions with a linear or oval appearance, with a smooth or verrucous texture, generally alopecic and with very variable color. Moreover, nevus sebaceous is one of the components of the so-called linear nevus syndrome or Schimmelpenning-Feuerstein-Mims syndrome, which is associated with multisystemic complications. The treatment of the lesions is still controversial; however, most experts indicate surgical excision as the most frequently adopted treatment method, in addition to multidisciplinary follow-up when the diagnosis of Schimmelpenning-Feuerstein-Mims syndrome is established. CONCLUSION: The linear nevus syndrome constitutes a rare manifestation; however, its diagnosis should be considered in children born with nevus sebaceous. There is no consensus yet on the best therapy, but surgical removal has shown to be a viable option.


Asunto(s)
Hamartoma , Nevo Pigmentado , Nevo Sebáceo de Jadassohn , Nevo , Neoplasias Cutáneas , Niño , Humanos , Masculino , Síndrome
15.
Spectrochim Acta A Mol Biomol Spectrosc ; 272: 120988, 2022 May 05.
Artículo en Inglés | MEDLINE | ID: mdl-35151165

RESUMEN

The preparation of metal@(dielectric or semiconductor) core@shell hybrid materials have been shown promising for both SERS and SEF applications due to improved stability in the presence of ions and the adsorbate compared to non-covered metallic nanoparticles. However, fine control over the thickness of the covering layer is essential to maximize the intrinsic trade-off between the plasmonic enhancement and the chemical stability improvement. Here, the preparation of manganese dioxide ultrathin layers covered gold nanorods (AuNR@MnO2) with varying thicknesses of the MnO2 layer is reported, and the characterization and evaluation of the resulting materials as SERS and SEF substrate. The MnO2 layer over the AuNR was prepared by reducing potassium permanganate by sodium oxalate in a basic medium. The AuNR@MnO2 hybrid material was characterized by UV-Vis spectroscopy, transmission electron microscopy, X-ray powder diffraction, and cyclic voltammetry. It was studied the SEF effect of the cyanine dye IR-820 excited at 785 nm with high performance for several thicknesses of the MnO2 ultrathin film. The enhancement factor increased for thicker oxide layers. The SERS effect of the IR-820 dye excited at 633 nm showed the most significant enhancement factor for thinner layers. The seemly opposite behavior of the two plasmonic effects may be assigned to the distance dependence of the electromagnetic field generated in the AuNR, which results in decreasing SERS performance. For SEF, the thinner layers resulted in the Au nanoparticles' emission quenching, so a more significant distance was necessary to observe enhancement.


Asunto(s)
Nanopartículas del Metal , Nanotubos , Oro/química , Compuestos de Manganeso/química , Nanopartículas del Metal/química , Nanotubos/química , Óxidos/química
16.
Online braz. j. nurs. (Online) ; 21(supl.2): e20226568, 21 janeiro 2022. tab, ilus
Artículo en Inglés, Español, Portugués | LILACS, BDENF - Enfermería | ID: biblio-1400272

RESUMEN

OBJETIVO: Descrever estratégias desenvolvidas para o enfrentamento da pandemia de COVID-19 em hospitais universitários. MÉTODO: Pesquisa descritiva, com abordagem quanti-qualitativa, desenvolvida a partir de um survey online com 104 enfermeiros de três hospitais universitários brasileiros. O processamento dos dados foi realizado por meio de análise textual com auxílio do software IRAMUTEQ®. RESULTADOS: Foram obtidas seis classes semânticas que representam as principais estratégias desenvolvidas para o enfrentamento da pandemia de COVID-19 no ambiente hospitalar: 1) Fornecimento de Equipamentos de Proteção Individual (17,2%); 2) Capacitações da equipe para o cuidado (18,8%); 3) Treinamento da equipe de apoio (15,6%); 4) Aquisição de equipamentos com boa qualidade (14,1%); 5) Definição de fluxos institucionais (20,5%) e 6) Promoção de apoio psicológico (14,1%). CONCLUSÃO: As estratégias elencadas pelos enfermeiros têm contribuído para a qualidade da assistência prestada aos pacientes, bem como a manutenção da saúde do trabalhador.


OBJECTIVE: To describe strategies developed to cope with the COVID-19 pandemic in university hospitals. METHOD: A descriptive research study with a quantitative and qualitative approach, developed from an online survey with 104 nurses from three Brazilian university hospitals. Data processing was performed through textual analysis with the aid of the IRAMUTEQ® software. RESULTS: Six semantic classes were obtained that represent the main strategies developed to cope with the COVID-19 pandemic in the hospital environment: 1) Provision of Personal Protective Equipment (17.2%); 2) Training of the team for the care to be provided (18.8%); 3) Training of the support team (15.6%); 4) Acquisition of good quality equipment (14.1%); 5) Definition of institutional flows (20.5%); and 6) Promotion of psychological support (14.1%). CONCLUSION: The strategies listed by the nurses have contributed to the quality of the care provided to the patients, as well as to preserving the workers' health.


OBJETIVO: Describir las estrategias que se desarrollaron en los hospitales universitarios para enfrentar la pandemia de COVID-19. MÉTODO: Investigación descriptiva, con enfoque cuantitativo y cualitativo, desarrollada a partir de survey online con 104 enfermeros de tres hospitales universitarios brasileños. El procesamiento de datos se realizó mediante análisis textual con la ayuda del software IRAMUTEQ®. RESULTADOS: Se obtuvieron seis clases semánticas que representan las principales estrategias desarrolladas para enfrentar la pandemia de COVID-19 en el ámbito hospitalario: 1) Suministro de Equipos de Protección Personal (17,2%); 2) Capacitación del equipo para la atención (18,8%); 3) Entrenamiento del equipo de apoyo (15,6%); 4) Adquisición de equipos de buena calidad (14,1%); 5) Definición de flujos institucionales (20,5%) y 6) Promoción de apoyo psicológico (14,1%). CONCLUSIÓN: Las estrategias enumeradas por los enfermeros han contribuido a la calidad de la atención que se les prestó a los pacientes y a mantener la salud de los trabajadores.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Estrategias de Salud , COVID-19 , Hospitales Universitarios/organización & administración
17.
Rev. bras. enferm ; 75(supl.1): e20201381, 2022. tab, graf
Artículo en Inglés | LILACS-Express | LILACS, BDENF - Enfermería | ID: biblio-1351719

RESUMEN

ABSTRACT Objective: to describe the changes implemented in the work environment of nurses in university hospitals considering the COVID-19 pandemic. Methods: this qualitative and descriptive research was developed from an online survey with 75 nurses from three Brazilian university hospitals. Data processing occurred through textual analysis with the aid of software IRAMUTEQ. Results: five semantic classes were obtained: Organization of units for exclusive care of patients with COVID-19; Adaptations in the use of personal protective equipment; Physical structure adaptation; Care flow institution; Increased number of beds and training courses. Final considerations: the results show the effort of healthcare and nursing professionals/managers in the development of structural adaptations and reorganizations of care processes, in the hospital context, to respond with quality and efficiency to the demands arising from the COVID-19 pandemic.


RESUMEN Objetivo: describir los cambios implementados en el ambiente laboral de enfermeras en hospitales universitarios ante la pandemia de COVID-19. Métodos: investigación cualitativa, descriptiva, desarrollada a partir de una encuesta en línea a 75 enfermeras de tres hospitales universitarios brasileños. El procesamiento de datos se realizó a través del análisis textual con la ayuda del software IRAMUTEQ. Resultados: se obtuvieron cinco clases semánticas: Organización de unidades para la atención exclusiva de pacientes con COVID-19; Adaptaciones en el uso de equipos de protección personal; Adaptación de la estructura física; Institución de flujos de servicios; Aumento del número de camas y cursos de formación. Consideraciones finales: los resultados muestran el esfuerzo de los profesionales/gestores del área de salud y enfermería en el desarrollo de adaptaciones estructurales y reorganizaciones de los procesos asistenciales, en el contexto hospitalario, para responder con calidad y eficiencia a las demandas derivadas de la pandemia de COVID-19.


RESUMO Objetivo: descrever as mudanças implementadas no ambiente de trabalho de enfermeiros em hospitais universitários diante da pandemia de COVID-19. Métodos: pesquisa qualitativa, do tipo descritiva, desenvolvida a partir de um survey online com 75 enfermeiros de três hospitais universitários brasileiros. O processamento dos dados ocorreu por meio de análise textual com auxílio do software IRAMUTEQ. Resultados: obtiveram-se cinco classes semânticas: Organização de unidades para atendimento exclusivo de pacientes com COVID-19; Adequações no uso de equipamentos de proteção individual; Adaptação da estrutura física; Instituição de fluxos de atendimento; Aumento do número de leitos e realização de capacitações. Considerações finais: os resultados evidenciam o esforço dos profissionais/gestores da área da saúde e enfermagem no desenvolvimento de adaptações estruturais e reorganizações dos processos assistenciais, no contexto hospitalar, para responder com qualidade e eficiência às demandas oriundas da pandemia de COVID-19.

18.
Trials ; 22(1): 886, 2021 Dec 06.
Artículo en Inglés | MEDLINE | ID: mdl-34872614

RESUMEN

BACKGROUND: The range of motion (RoM) of dorsiflexion (DF) plays an important role in human mobility, such as absorption of body weight during gait deceleration, jump landings, balance, and eccentric movements. This limitation can generate potentially damaging movements. This way, evaluating techniques for DF RoM increase could help improve immediate performance in such functional activities. This being the case, the objective of this study will be to verify the sum effect of different joint mobilization techniques for DF gain in persons practicing physical activities and its relationship with functional performance and balance. METHODOLOGY: This is a randomized, controlled, and blind clinical trial. Fifty-four (54) volunteers will be recruited, aged between 18 and 40 years, who have DF limitations. After checking eligibility criteria, the participants will be submitted to a physiotherapeutic evaluation. A researcher, blind to evaluation and treatment, will perform the randomization of patients in groups: (A) Joint Mobilization - Mulligan Concept and (B) Joint Mobilization - Maitland Method. All volunteers will be submitted by two blind evaluators for randomization and treatment groups. They will realize the initial evaluation (A0), immediately after techniques (A1) and after 3-4 days of the technique application (A2). A different researcher, blind for evaluation, will perform the treatment, according to the randomization group. DISCUSSION: It is already known that DF RoM limitation can lead to compensatory and potentially damaging lower limb movements and that joint mobilizations are effective to treatment. However, there is no consensus whether the application of these techniques would also improve aspects of dynamic postural balance and performance in individuals practicing physical activity, and whether the sum of two joint mobilization techniques could enhance this effect. TRIAL REGISTRATION: Brazilian Registry of Clinical Trials (ReBEC) RBR-93xv9t . Registered on 09 April 2020.


Asunto(s)
Tobillo , Manipulaciones Musculoesqueléticas , Adolescente , Adulto , Articulación del Tobillo , Humanos , Equilibrio Postural , Ensayos Clínicos Controlados Aleatorios como Asunto , Rango del Movimiento Articular , Adulto Joven
19.
Rev Bras Enferm ; 75(suppl 1): e20201381, 2021.
Artículo en Inglés, Portugués | MEDLINE | ID: mdl-34852037

RESUMEN

OBJECTIVE: to describe the changes implemented in the work environment of nurses in university hospitals considering the COVID-19 pandemic. METHODS: this qualitative and descriptive research was developed from an online survey with 75 nurses from three Brazilian university hospitals. Data processing occurred through textual analysis with the aid of software IRAMUTEQ. RESULTS: five semantic classes were obtained: Organization of units for exclusive care of patients with COVID-19; Adaptations in the use of personal protective equipment; Physical structure adaptation; Care flow institution; Increased number of beds and training courses. Final considerations: the results show the effort of healthcare and nursing professionals/managers in the development of structural adaptations and reorganizations of care processes, in the hospital context, to respond with quality and efficiency to the demands arising from the COVID-19 pandemic.


Asunto(s)
COVID-19 , Enfermeras y Enfermeros , Humanos , Pandemias , Equipo de Protección Personal , SARS-CoV-2 , Lugar de Trabajo
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